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1

Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

Steven M. Sine, Kinji Ohno, Cecilia Bouzat, Anthony Auerbach, Margherita Milone, Jerry N. Pruitt, Andrew G. Engel

Journal:

Year:

1995

Language:

english

File:

PDF, 1.32 MB

english, 1995

2

An intrinsic GABAergic system in human lymphocytes

Leonardo Dionisio, María José De Rosa, Cecilia Bouzat, María del Carmen Esandi

Journal:

Neuropharmacology

Year:

2011

Language:

english

File:

PDF, 589 KB

english, 2011

3

Molecular function of α7 nicotinic receptors as drug targets

Bouzat, Cecilia, Lasala, Matías, Nielsen, Beatriz Elizabeth, Corradi, Jeremías, Esandi, María del Carmen

Journal:

The Journal of Physiology

Year:

2017

Language:

english

File:

PDF, 5.82 MB

english, 2017

4

Flavonoids as positive allosteric modulators of α7 nicotinic receptors

Nielsen, Beatriz Elizabeth, Bermudez, Isabel, Bouzat, Cecilia

Journal:

Neuropharmacology

Year:

2019

Language:

english

File:

PDF, 5.03 MB

english, 2019

5

End-plate acetylcholine receptor deficiency due to nonsense mutations in the ε subunit

Dr Andrew G. Engel, Kinji Ohno, Cecilia Bouzat, Steven M. Sine, Robert C. Griggs

Journal:

Annals of Neurology

Year:

1996

Language:

english

File:

PDF, 804 KB

english, 1996

6

Effects of static magnetic fields on nicotinic cholinergic receptor function

María Fernanda Tolosa, Cecilia Bouzat, Walter Rubén Cravero

Journal:

Bioelectromagnetics

Year:

2011

Language:

english

File:

PDF, 649 KB

english, 2011

7

Nongenomic effects of steroids on the nicotinic acetylcholine receptor

Barrantes, Francisco J, Antollini, Silvia S, Bouzat, Cecilia B, Garbus, Ingrid, Massol, Ramiro H

Journal:

Kidney International

Year:

2000

Language:

english

File:

PDF, 1.39 MB

english, 2000

8

Changes in channel properties of acetylcholine receptors during the time course of thiol chemical modifications

Cecilia Bouzat, Francisco J. Barrantes, Frederick J. Sigworth

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1991

Language:

english

File:

PDF, 1.17 MB

english, 1991

9

Effect of chemical modification of extracellular histidyl residues on the channel properties of the nicotinic acetylcholine receptor

Cecilia B. Bouzat, H. Daniel Lacorazza, Mirtha Biscoglio Jiménez Bonino, Francisco J. Barrantes

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1993

Language:

english

File:

PDF, 743 KB

english, 1993

10

Structural Basis of Activation of Cys-Loop Receptors: the Extracellular–Transmembrane Interface as a Coupling Region

Mariana Bartos, Jeremías Corradi, Cecilia Bouzat

Journal:

Molecular Neurobiology

Year:

2009

Language:

english

File:

PDF, 4.09 MB

english, 2009

11

The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms

Guillermo Spitzmaul, Fernanda Gumilar, James P Dilger, Cecilia Bouzat

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.73 MB

english, 2009

12

An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition at the synapse

Almedom, Ruta B, Liewald, Jana F, Hernando, Guillermina, Schultheis, Christian, Rayes, Diego, Pan, Jie, Schedletzky, Thorsten, Hutter, Harald, Bouzat, Cecilia, Gottschalk, Alexander

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 2.57 MB

english, 2009

13

Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel

Bouzat, Cecilia, Gumilar, Fernanda, Spitzmaul, Guillermo, Wang, Hai-Long, Rayes, Diego, Hansen, Scott B., Taylor, Palmer, Sine, Steven M.

Journal:

Year:

2004

Language:

english

File:

PDF, 758 KB

english, 2004

14

Key roles of hydrophobic rings of TM2 in gating of the α9α10 nicotinic cholinergic receptor

Paola V Plazas, María J De Rosa, María E Gomez-Casati, Miguel Verbitsky, Noelia Weisstaub, Eleonora Katz, Cecilia Bouzat, Ana Belén Elgoyhen

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 314 KB

english, 2005

15

Inherited and experimentally induced changes in gating kinetics of muscle nicotinic acetylcholine receptor

Cecilia Bouzat, Francisco J. Barrantes

Journal:

Journal of Molecular Neuroscience

Year:

1999

Language:

english

File:

PDF, 273 KB

english, 1999

16

Tricyclic antidepressants inhibit homomeric Cys-loop receptors by acting at different conformational states

Fernanda Gumilar, Cecilia Bouzat

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 678 KB

english, 2008

17

Relationship between α7 nAChR and apoptosis in human lymphocytes

María José De Rosa, María del Carmen Esandi, Andrés Garelli, Diego Rayes, Cecilia Bouzat

Journal:

Journal of Neuroimmunology

Year:

2005

Language:

english

File:

PDF, 471 KB

english, 2005

18

New insights into the structural bases of activation of Cys-loop receptors

Journal:

Journal of Physiology-Paris

Year:

2012

Language:

english

File:

PDF, 843 KB

english, 2012

19

Subunit-selective role of the M3 transmembrane domain of the nicotinic acetylcholine receptor in channel gating

María José De Rosa, Jeremías Corradi, Cecilia Bouzat

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2008

Language:

english

File:

PDF, 790 KB

english, 2008

20

Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors

Hugo R. Arias, Pankaj Bhumireddy, Cecilia Bouzat

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2006

Language:

english

File:

PDF, 912 KB

english, 2006

21

Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation

María José De Rosa, Leonardo Dionisio, Evangelina Agriello, Cecilia Bouzat, María del Carmen Esandi

Journal:

Year:

2009

Language:

english

File:

PDF, 313 KB

english, 2009

22

The anthelmintic pyrantel acts as a low efficacious agonist and an open-channel blocker of mammalian acetylcholine receptors

Diego Rayes, Marı́a José De Rosa, Guillermo Spitzmaul, Cecilia Bouzat

Journal:

Neuropharmacology

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

23

Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants

Fernanda Gumilar, Hugo R Arias, Guillermo Spitzmaul, Cecilia Bouzat

Journal:

Neuropharmacology

Year:

2003

Language:

english

File:

PDF, 796 KB

english, 2003

24

Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors

Cecilia Bouzat, Nina Bren, Steven M. Sine

Journal:

Year:

1994

Language:

english

File:

PDF, 1.00 MB

english, 1994

25

Subunit-Selective Contribution to Channel Gating of the M4 Domain of the Nicotinic Receptor

Bouzat, Cecilia, Gumilar, Fernanda, del Carmen Esandi, María, Sine, Steven M.

Journal:

Biophysical Journal

Year:

2002

Language:

english

File:

PDF, 259 KB

english, 2002

26

Electrical Fingerprinting Reveals Agonist Binding Sites Required for Activation of Homo-pentameric Cys-loop Receptors

Bouzat, Cecilia B., Rayes, Diego, De Rosa, Maria Jose, Sine, Steven M.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

27

Single-Channel Kinetic Analysis for Activation and Desensitization of Homomeric 5-HT3A Receptors

Corradi, Jeremías, Gumilar, Fernanda, Bouzat, Cecilia

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

28

A Novel Mechanism of Modulation of 5-HT3A Receptors by Hydrocortisone

Corradi, Jeremías, Andersen, Natalia, Bouzat, Cecilia

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 1.39 MB

english, 2011

29

Role of Pairwise Interactions between M1 and M2 Domains of the Nicotinic Receptor in Channel Gating

Corradi, Jeremías, Spitzmaul, Guillermo, De Rosa, María José, Costabel, Marcelo, Bouzat, Cecilia

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 875 KB

english, 2007

30

GABAA receptor plasticity in Jurkat T cells

Dionisio, Leonardo, Arias, Verónica, Bouzat, Cecilia, Esandi, María del Carmen

Journal:

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

31

Interaction of Bupropion with Muscle-Type Nicotinic Acetylcholine Receptors in Different Conformational States

Arias, Hugo R., Gumilar, Fernanda, Rosenberg, Avraham, Targowska-Duda, Katarzyna M., Feuerbach, Dominik, Jozwiak, Krzysztof, Moaddel, Ruin, Wainer, Irving W., Bouzat, Cecilia

Journal:

Year:

2009

Language:

english

File:

PDF, 2.14 MB

english, 2009

32

Differential Pharmacological Activity of JN403 between α7 and Muscle Nicotinic Acetylcholine Receptors

Arias, Hugo R., De Rosa, Maria Jose, Bergé, Ignacio, Feuerbach, Dominik, Bouzat, Cecilia

Journal:

Year:

2013

Language:

english

File:

PDF, 2.88 MB

english, 2013

33

Molecular Mechanisms and Binding Site Location for the Noncompetitive Antagonist Crystal Violet on Nicotinic Acetylcholine Receptors †

Arias, Hugo R., Bhumireddy, Pankaj, Spitzmaul, Guillermo, Trudell, James R., Bouzat, Cecilia

Journal:

Year:

2006

Language:

english

File:

PDF, 311 KB

english, 2006

34

Number of Extracellular-Transmembrane Interfaces Required for Activation of Homomeric Cys-Loop Receptors

Andersen, Natalia, Corradi, Jeremias, Bartos, Mariana, Sine, Steven M., Bouzat, Cecilia B.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

35

Contribution of Agonist Binding Sites and Coupling Regions to Activation and Desensitization of Homomeric Cys-Loop Receptors

Bouzat, Cecilia B., Andersen, Natalia D., Corradi, Jeremias, Sine, Steven M.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 34 KB

english, 2012

36

A Novel Mechanism for the Inhibitory Action of Hydrocortisone at 5-HT3A Receptor

Andersen, Natalia, Corradi, Jeremias, Bouzat, Cecilia B.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

37

Mechanistic Basis of Partial Agonism at 5-HT3A Receptors

Corradi, Jeremías, Bouzat, Cecilia

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

38

Stoichiometry for Activation of Neuronal α7 Nicotinic Receptors

Andersen, Natalia, Corradi, Jeremias, Sine, Steven, Bouzat, Cecilia B.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

39

Single-Channel Kinetic Analysis for Activation and Desensitization of Homomeric 5-HT3A Receptors

Corradi, Jeremias, Gumilar, Fernanda, Bouzat, Cecilia B.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

40

Mechanistic contributions of residues in the M1 transmembrane domain of the nicotinic receptor to channel gating

Spitzmaul, Guillermo, Corradi, Jeremías, Bouzat, Cecilia

Journal:

Molecular Membrame Biology

Year:

2004

Language:

english

File:

PDF, 443 KB

english, 2004

41

Electromagnetic Fields Inhibit Cys-Loop Receptor Function by Inducing a Novel Conformational State

Tolosa, Fernanda, Cravero, Walter R., Bouzat, Cecilia B.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

42

5-HT 3 Receptor Brain-Type B-Subunits are Differentially Expressed in Heterologous Systems

Corradi, Jeremias, Thompson, Andrew J., McGonigle, Ian, Price, Kerry. L., Bouzat, Cecilia, Lummis, Sarah C. R.

Journal:

ACS Chemical Neuroscience

Year:

2015

Language:

english

File:

PDF, 2.27 MB

english, 2015

43

Congenital Myasthenic Syndrome Caused by Prolonged Acetylcholine Receptor Channel Openings Due to a Mutation in the M2 Domain of the ε Subunit

Kinji Ohno, David O. Hutchinson, Margherita Milone, Joan M. Brengman, Cecilia Bouzat, Steven M. Sine and Andrew G. Engel

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 937 KB

english, 1995

44

Exploring the Positive Allosteric Modulation of Human α7 Nicotinic Receptors from a Single-Channel Perspective

Andersen, Natalia D., Nielsen, Beatriz E., Corradi, Jeremías, Tolosa, María F., Feuerbach, Dominik, Arias, Hugo R., Bouzat, Cecilia

Journal:

Neuropharmacology

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

45

Assigning functions to residues in the acetylcholine receptor channel region (Review)

Bouzat, Cecilia, Barrantes, Francisco J.

Journal:

Molecular Membrame Biology

Year:

1997

Language:

english

File:

PDF, 1.33 MB

english, 1997

46

Steroids differentially inhibit the nicotinic acetylcholine receptor

Garbus, Ingrid, Bouzat, Cecilia, Barrantes, Francisco J.

Journal:

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

47

Amphetamine acts as a channel blocker of the acetylcholine receptor

Spitzmaul, Guillermo F., del Carmen Esandi, María, Bouzat, Cecilia

Journal:

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

48

Ephedrine blocks wild-type and long-lived mutant acetylcholine receptor channels

Bouzat, Cecilia

Journal:

Year:

1996

Language:

english

File:

PDF, 89 KB

english, 1996

49

Exploring Alpha7 Positive Allosteric Modulators from a Single-Channel Perspective

Andersen, Natalia D., Corradi, Jeremias, Tolosa, Fernanda, Gasparini, Nehuen, Arias, Hugo R., Bouzat, Cecilia B.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 46 KB

english, 2015

50

Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-Stimulated NK Cells

Zanetti, Samanta R., Ziblat, Andrea, Torres, Nicolás I., Zwirner, Norberto W., Bouzat, Cecilia

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.35 MB

english, 2016